R-3-Aminobutanol
R-3-Aminobutanol (R-3-amino-1-butanol), CAS No.: 61477-40-5, is an important raw material for the treatment of AIDS, drug dolutegravir. It plays an important role in the introduction and construction of chiral functional groups in dolutegravir, and the quality and price of the product have a great influence on the quality and cost of dolutegravir. In addition, R-3-aminobutanol is an intermediate of antitumor drug 4-methylcyclophosphamide. It can also be derived from β-lactam as an important intermediate in the synthesis of penicillenes. There are chemical resolution, chemical induction, synthesis of chiral materials and preparative chromatography.
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